CancerSymptoms.org

Peripheral Neuropathy
What is Peripheral Neuropathy?

Peripheral neuropathy is a disorder resulting from injury to peripheral nerves. Peripheral neuropathy is inflammation, injury, or deterioration of the peripheral nerve fibers. Peripheral neuropathy can occur as a side effect of cancer treatment. 1, 11 However, there are other common causes of peripheral neuropathy that are unrelated to cancer, including:

  • Diabetes mellitus
  • Nutritional imbalances, especially vitamin B12 or B6 deficiencies
  • Some kidney diseases
  • Alcohol abuse
  • HIV/AIDS
  • Lead poisoning
  • Hypothyroidism
  • Auto-immune disorders
  • Hereditary peripheral neuropathies (such as Charcot-Marie Toothe disease)
  • Medications including anti-tuberculosis medications such as isoniazid or ethambutol; antibiotics such as gentamycin or ciprofloxacin; phenytion used to control seizures
  • Atherosclerosis/ ischemic disease (blood vessel and/or heart disease)